Wedstrijdprogramma 12 – 15 mei
| Datum | Tijd | Thuis team | Uit team | Accommodatie |
| 12-05-2022 | 20:30:00 | KRAS/Volendam HS2 | IMTO Benelux/Hellas HS1 | Opperdam |
| 14-05-2022 | 10:00:00 | VENECO/VELO F1 | Hellas F2 | VELO/Wateringen (V) |
| 14-05-2022 | 12:15:00 | Verburch F3 | Hellas F4 | Verburch (V) |
| 14-05-2022 | 13:10:00 | Verburch E2# | Hellas E2 | Verburch (V) |
| 14-05-2022 | 13:10:00 | Verburch D2 | Hellas D2 | Verburch (V) |
| 14-05-2022 | 14:35:00 | HV Quintus D1# | Hellas D1# | Quintus/Kwintsheul (V) |
| 14-05-2022 | 19:00:00 | The Dome /Handbal Houten HS1 | IMTO Benelux/Hellas HS1 | Sporthal The Dome |
| 14-05-2022 | 20:00:00 | Apollo HS1 | IMTO Benelux/Hellas HS2 | De Landing |
| 14-05-2022 | 20:00:00 | Hellas DS1 | United Breda/Orion R DS1 | Hellashal |
| 15-05-2022 | 09:30:00 | Hellas F3 | Foreholte F2# | Hellas (V) |
| 15-05-2022 | 09:30:00 | Hellas F1# | ODIS F1 | Hellas (V) |
| 15-05-2022 | 10:25:00 | Hellas E1 | WPK/Westlandia E2 | Hellas (V) |
| 15-05-2022 | 11:25:00 | Hellas E3# | HVV’70 E1# | Hellas (V) |
| 15-05-2022 | 11:45:00 | Dynamico HA1 | IMTO Benelux/Hellas HA1 | Mondriaanhal |
| 15-05-2022 | 12:25:00 | Hellas D3 | Hercules D4 | Hellas (V) |
| 15-05-2022 | 12:45:00 | Oliveo HC2 | Hellas HC2 | Oliveo/Het Nest (V) |
| 15-05-2022 | 13:10:00 | EHC HC2 | Hellas HC1# | EHC/Sportpark Westvliet (V) |
| 15-05-2022 | 13:20:00 | Hellas DC1# | TOGB DC1 | Hellas (V) |
| 15-05-2022 | 13:30:00 | Hellas DA1 | Z.A.P. DA1 | Hellashal |
| 15-05-2022 | 14:25:00 | Hellas DB1 | DIOS DB1 | Hellas (V) |
| 15-05-2022 | 14:25:00 | VENECO/VELO E9 | Hellas E4 | VELO/Wateringen (V) |
| 15-05-2022 | 15:00:00 | Hellas HS3 | Feyenoord Handbal HS2 | Hellashal |
| 15-05-2022 | 15:10:00 | WPK/Westlandia HB1 | Hellas HB1 | Westlandia/Sportpark De Hoge Bomen |
| 15-05-2022 | 15:30:00 | Hellas DS1 | Olympia’72 DS1 | Hellas (V) |
| 15-05-2022 | 16:00:00 | HV Quintus DC3# | Hellas DC2# | Quintus/Kwintsheul (V) |