Wedstrijdprogramma 20-21 november
| Datum | Tijd | Thuis team | Uit team | Accommodatie |
| 20-11-2021 | 09:00:00 | Hellas F1 | Hercules F1 | Hellashal |
| 20-11-2021 | 09:00:00 | Hellas F2 | Verburch F1# | Hellashal |
| 20-11-2021 | 10:00:00 | Hellas E4 | Oliveo E3 | Hellashal |
| 20-11-2021 | 10:45:00 | Foreholte F2# | Hellas F4 | De Tulp |
| 20-11-2021 | 11:00:00 | Hellas E3# | Gemini (Z) E2 | Hellashal |
| 20-11-2021 | 12:00:00 | Hellas D3 | ODIS D2 | Hellashal |
| 20-11-2021 | 13:00:00 | Hellas D1# | VENECO/VELO D2 | Hellashal |
| 20-11-2021 | 19:00:00 | IMTO Benelux/Hellas HA1 | Feyenoord Handbal HA1 | Hellashal |
| 20-11-2021 | 19:00:00 | Klaverblad/Oliveo DS1 | Hellas DS1 | Het Nest |
| 20-11-2021 | 21:00:00 | IMTO Benelux/Hellas HS1 | KRAS/Volendam HS2 | Hellashal |
| 21-11-2021 | 09:45:00 | Hellas DC1# | VENECO/VELO DC2 | Hellashal |
| 21-11-2021 | 10:25:00 | Northa DC1# | Hellas DC2# | Duinwetering sporthallen |
| 21-11-2021 | 10:25:00 | EHC E1 | Hellas E2 | EHC-European Sports Dome |
| 21-11-2021 | 10:50:00 | Hellas HB1 | De Meeuwen HB1# | Hellashal |
| 21-11-2021 | 11:25:00 | Stompwijk’92 D2 | Hellas D4 | Sporthal Meerhorst |
| 21-11-2021 | 12:00:00 | Hellas DB1# | TOGB DB1# | Hellashal |
| 21-11-2021 | 12:20:00 | DIOS DS1 | Hellas DS2 | Ballonhal |
| 21-11-2021 | 12:35:00 | OTTO Work Force/VOC Amsterdam DA1 | Hellas DA1 | Sporthal Elzenhagen |
| 21-11-2021 | 12:40:00 | Rijnstreek D1# | Hellas D2 | Limeshal |
| 21-11-2021 | 13:30:00 | IMTO Benelux/Hellas HS2 | handbalshop.nl/Witte Ster HS1 | Hellashal |
| 21-11-2021 | 13:30:00 | VENECO/VELO E1 | Hellas E1 | Velohal |
| 21-11-2021 | 13:45:00 | Schipluiden F1# | Hellas F3 | Postkogekohal |
| 21-11-2021 | 14:00:00 | DIOS HS1 | Hellas HS3 | Ballonhal |
| 21-11-2021 | 14:50:00 | Hellas HS4 | EHC HS2 | Hellashal |
| 21-11-2021 | 16:10:00 | Hellas DS3 | Warmunda DS1 | Hellashal |