Wedstrijdprogramma 27-28 november
| Datum | Tijd | Thuis team | Uit team | Accommodatie |
| 27-11-2021 | 09:00:00 | Hellas F3 | WHC (Den Haag) F1 | Hellashal |
| 27-11-2021 | 09:00:00 | Hellas F4 | Verburch F3 | Hellashal |
| 27-11-2021 | 10:00:00 | Hellas E2 | VENECO/VELO E3 | Hellashal |
| 27-11-2021 | 10:50:00 | DIOS F1 | Hellas F2 | Ballonhal |
| 27-11-2021 | 11:00:00 | Hellas E1 | Gemini (Z) E1 | Hellashal |
| 27-11-2021 | 12:05:00 | Hellas D4 | Hercules D5 | Hellashal |
| 27-11-2021 | 13:00:00 | Hellas D2 | DIOS D1 | Hellashal |
| 27-11-2021 | 13:35:00 | Verburch DC1 | Hellas DC1# | J.v.d.Valkhal |
| 27-11-2021 | 13:45:00 | DIOS E2# | Hellas E3# | Ballonhal |
| 27-11-2021 | 18:30:00 | Hellas DS2 | WHC (Den Haag) DS1 | Hellashal |
| 27-11-2021 | 18:30:00 | DWS HB1 | Hellas HB1 | Groenoordhal |
| 27-11-2021 | 19:00:00 | Green Park/Handbal Aalsmeer HA1 | IMTO Benelux/Hellas HA1 | Sporthal de Bloemhof |
| 27-11-2021 | 20:00:00 | Hellas DS1 | MEOS DS1 | Hellashal |
| 27-11-2021 | 20:45:00 | Houten HS2 | IMTO Benelux/Hellas HS2 | Sporthal The Dome |
| 27-11-2021 | 21:00:00 | Feyenoord Handbal HS1 | IMTO Benelux/Hellas HS1 | Wielewaal |
| 28-11-2021 | 09:00:00 | WPK/Westlandia DB2 | Hellas DB1# | De Pijl |
| 28-11-2021 | 10:00:00 | EHC D2 | Hellas D3 | EHC-European Sports Dome |
| 28-11-2021 | 10:00:00 | ODIS F1 | Hellas F1 | Vreeloohal |
| 28-11-2021 | 10:50:00 | Hellas HC2 | Drechtsteden HC1# | Hellashal |
| 28-11-2021 | 11:40:00 | Foreholte D1 | Hellas D1# | De Tulp |
| 28-11-2021 | 11:55:00 | Hellas DC2# | Foreholte DC1 | Hellashal |
| 28-11-2021 | 13:15:00 | Warmunda/MSV HS1 | Hellas HS4 | De Geest |
| 28-11-2021 | 13:30:00 | Hellas DA1 | Feyenoord Handbal DA1 | Hellashal |
| 28-11-2021 | 14:20:00 | Verburch DS2 | Hellas DS3 | J.v.d.Valkhal |
| 28-11-2021 | 15:00:00 | Hellas HS3 | Van Tiel/Ventura HS1 | Hellashal |